Feng Lab

Principal Investigator

Yuliang Feng

Yuliang Feng is an Associate Professor and PhD supervisor in the Department of Pharmacology, Southern University of Science and Technology. He received his Bachelor of Medicine from Sun Yat-sen University, Doctor of Medicine from Southern Medical University and Doctor of Philosophy from Oxford University. He is a postdoctoral fellow at the Department of Pathology, University of Cincinnati, the Department of Molecular Biology, Radboud University, Nijmegen, the Netherlands, and the Jackson Laboratory, USA. He is committed to using novel 3D genomic/epigenomic technologies to reveal the transcriptional regulation mechanisms of human diseases, especially cardiovascular diseases and tumourigenesis, and has participated in large-scale 3D genomic and epigenomic projects such as NIH ENCODE (Encyclopedia of DNA Elements), 4DN (4D Nucleome), and BLUEPRINT (Europe). projects. He has been published in leading international academic journals, Such as Circulation, Gastroenterology, Advanced Genetics, Nature Communications, Nucleic Acids Research, Science Advances, Theranostics, Basic Research in Cardiology, Protein&Cell and other more than 40 papers.

Team

Liuyang Cai

Postdoc, Bioinformatics

Ph.D. The Chinese University of Hong Kong

Liuyang is developing softwares to explore and visualize multi-omics sequencing data. By mining extensive public datasets, including Hi-C, HiChIP, and single cell data, he aims to understand transcriptional regulatory abnormalities in the progression of cardiovascular diseases and cancer.

Ziqing Yin

Postdoc, Biology

Ph.D., European Research Institute for the Biology of Ageing,University of Groningen

Ziqing has a particular interest in aging, especially in how age-related changes in 3D genome and epigenome influence cardiovascular health. His interdisciplinary background enables him to contribute a unique perspective to the lab’s research.

Jun Qiao

PhD Student, Biology

Master of Internal Medicine, Shanxi Medical University

Jun is focused on developing and implementing methods to can help us understand the shared genetic mechanisms between cardiovascular diseases and diseases across various other systems.

Pengwei Zhang

PhD Student, Biology

Master of Science, Jinan University

Pengwei is studying how TFs’ transcriptional regulation and 3D genome organization in the failing heart. By mapping epigenome, RNA expression and 3D genome architecture in the single nuclei, he aims to understand the mechanism of heart failure at single cell level.

Ruixin Zhou

Master Student, Biology

Bachelor of Medicine, Southern Medical University

Ruixin is focused on finding the Hub RNA that mediates changes in three-dimensional chromatin conformation in heart failure. By exploring the RNA binding sites on the genome and chromatin interactions, she aims to discover new therapeutic targets for heart failure.

Chang Shu

Master Student, Biology

Bachelor of Science, South China Agricultural University

Chang is learning about 3D epigenomics experiments and related bioinformatics techniques, and he is intrigued by everything in the laboratory.

Yelan li

Research assistant

Master of Science, Shaanxi Normal University

Yelan is focused on dissecting the evolution dynamics of cross-species 3D genome of heart. By constructing three-dimensional genetic maps of different species, she aim to understand the theoretical breakthroughs in the mechanisms of species evolution and biological development.

Shiyu Zheng

Research assistant

Bachelor of Clinical Pharmacy, Southern Medical University

Shiyu, mainly handle the daily management of the lab.

Yong Huang

Visiting student

Ph.D. Huazhong University of Science and Technology

Yong is a gynecologist exploring the potential links between metabolic diseases and gynecological tumors by investigating changes in three-dimensional chromatin conformation

Yuzhe Fan

Visiting student

Master of Clinical Medicine, Anhui Medical University

Yuzhe is focused on discovering the interaction between the cardiovascular system and gut microbiota through metagenomic analysis.

Xinyi Wang

Visiting student

Bachelor of Medicine, Nanchang University

Xinyi is focused on editing base or regulatory element on noncoding region through CRISPR/Cas9 and exploring its relationship to cardiovascular disease.