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  • Publications
    2024
    EXPRESSO: a multi-omics database to explore multi-layered 3D genomic organization
    Nucleic Acids Res
    Cai L, Qiao J, Zhou R, Wang X, Li Y, Jiang L, Zhou Q*, Li G*, Xu T*, Feng Y*
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    Genetic analyses identify shared genetic components related to autoimmune and cardiovascular diseases
    medRxiv
    Jun Qiao, Minjing Chang, Miaoran Chen, Yuhui Zhao, Jiawei Hao, Pengwei Zhang, Ruixin Zhou, Liuyang Cai, Feng Liu, Xiaoping Fan,Siim Pauklin, Rongjun Zou, Zhixiu Li, Yuliang Feng*
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    Disentangling shared genetic etiologies for kidney function and cardiovascular diseases
    medRxiv
    Jun Qiao, Kaixin Yao, Yujuan Yuan, Xichen Yang, Le Zhou, Yinqi Long, Miaoran Chen, Wenjia Xie, Yixuan Yang, Yangpo Cao, Siim Pauklin*, Jinguo Xu*, Yining Yang*,Yuliang Feng*
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    Therapeutic protein targets for cardiometabolic diseases: Mendelian randomization integrating plasma proteomes with genome-wide association data
    PREPRINT (Version 1) available at Research Square
    Ruixin Zhou, Jun Qiao, Liuyang Cai, Siim Pauklin*, Yuliang Feng*
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    Contribution of leukocyte telomere length to major cardiovascular diseases onset: phenotypic and genetic insights from a large-scale genome-wide cross-trait analysis
    medRxiv
    Jun Qiao, Qian Wang, Yuhui Zhao, Minjing Chang, Liuyang Cai, Feng Liu, Kaixin Yao, Leilei Zheng, Ning Tan, Pengcheng He, Anil G. Jegga, Siim Pauklin*, Lei Jiang*, Yining Yang*,Yuliang Feng*
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    Targeted modulation of intestinal epithelial regeneration and immune response in ulcerative colitis using dual-targeting bilirubin nanoparticles
    Theranostics
    Zhuo Z, Guo K, Luo Y, Yang Q, Wu H, Zeng R, Jiang R, Li J, Wei R, Lian Q*, Sha W*, Feng Y*, Chen H*
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    2023
    BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
    Gastroenterology
    Feng Y#, Cai L#, Pook M#, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, Jegga AG, Oppermann U, Wang Y*, Huang W*, Jiang L*
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    Shared Genetic Architecture Contributes to Risk of Major Cardiovascular Diseases
    PREPRINT (Version 1) available at Research Square
    Jun Qiao, Liuyang Cai, Minjing Chang, Can Wang, Rong Zhao, Shan Song, Ning Tan, Pengcheng He*, Siim Pauklin*, Lei Jiang*, Yuliang Feng*
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    Genetic risk, adherence to healthy lifestyle and acute cardiovascular and thromboembolic complications following SARS-COV-2 infection
    Nat Commun
    Xie J#, Feng Y#, Newby D, Zheng B, Feng Q, Prats-Uribe A, Li C, Wareham NJ, Paredes R, Prieto-Alhambra D*
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    Associations of habitual glucosamine use with SARS-CoV-2 infection and hospital admission and death with COVID-19: Evidence from a large population based cohort study
    J Med Virol
    Meng M, Wu Y, Sha W, Zeng R, Luo D, Jiang R, Wu H, Zhuo Z, Yang Q, Li J, Leung FW*, Duan C*, Feng Y*, Chen H*
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    2022
    Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy
    Circulation
    Feng Y#, Cai L#, Hong W#, Zhang C#, Tan N, Wang M, Wang C, Liu F, Wang X, Ma J, Gao C, Kumar N, Mo Y, Geng Q, Luo C, Lin Y, Chen H, Wang S, Watson M, Jegga A, Pedersen R, Fu J, Wang Z, Fan G, Sadayappan S, Wang Y, Pauklin S*, Huang F*, Huang W*, Jiang L*
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    3D-Epigenomic Regulation of Gene Transcription in Hepatocellular Carcinoma Cells
    Adv Genet
    Feng Y#, Wang P#, Cai L#, Zhan M#, He F, Wang J, Li Y, Gega E, Li S, Zhang W, Zhao W, Xin Y, He X, Chen X*, Ruan Y, Lu L*
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    3D chromatin architecture and transcription regulation in cancer
    J Hematol Oncol
    Deng S, Feng Y, Pauklin S*
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    2021
    Mitochondrial nucleoid in cardiac homeostasis: bidirectional signaling of mitochondria and nucleus in cardiac diseases
    Basic Res Cardiol
    Feng Y#, Huang W#, Paul C, Liu X, Sadayappan S, Wang Y*, Pauklin S*
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    Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatic cholangiocarcinoma
    Genomics
    He K#,Feng Y#, An S#, Liu F, Xiang G*
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    In situ Chromatin Interaction Analysis Using Paired‐End Tag Sequencing
    Curr Protoc
    Wang P, Feng Y, Zhu K, Chai H, Chang YT, Liu X, Shen C, Gega E, Li B, Kim M, Ruan X, Ruan Y*
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    Subcellular Localization of miRNAs and Implications in Cellular Homeostasis
    Genes (Basel)
    Jie M, Feng T, Huang W, Zhang M, Feng Y*#, Jiang H*, Wen Z*
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    Phosphodiesterase-5 inhibitors in Men with Stable Coronary Artery Disease
    J Am Coll Cardiol
    Wen Z*, Feng Y, Jiang L
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    PAF1 regulates the stemness of pancreatic cancer stem cells
    Gastroenterology
    Feng Y, Mouti M and Pauklin S*
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    Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B
    J Hepatol
    Wen Z*#, Feng Y# and Yan X
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    3D chromatin architecture and epigenetic regulation in cancer stem cell
    Protein Cell
    Feng Y, Liu X and Pauklin S*
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    2020
    ChIA-PIPE: A fully automated pipeline for comprehensive ChIA-PET data analysis and visualization
    Sci Adv
    Lee B, Wang J, Cai L, Kim M, Namburi S, Tjong H, Feng Y, Wang P, Tang Z, Abbas A, Wei CL*, Ruan Y* and Li S*
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    Targeting TGFbeta Signalling in Cancer: Toward Context-Specific Strategies
    Trends Cancer
    French R#, Feng Y# and Pauklin S*
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    Two Sides of the Same Coin: The Roles of Transforming Growth Factor-beta in Colorectal Carcinogenesis
    Gastroenterology
    Feng Y and Pauklin S*
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    Demystifying Cancer Etiology via 3D Genome Mapping
    Trends Genet
    Feng Y and Pauklin S*
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    Revisiting 3D chromatin architecture in cancer development and progression
    Nucleic Acids Res
    Feng Y and Pauklin S*
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    2018
    Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential
    Exp Cell Res
    Huang W#, Liang J#, Feng Y#, Jia Z, Jiang L, Cai W, Paul C, Gu JG, Stambrook PJ, Millard RW, Zhu XL, Zhu P* and Wang Y*
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    Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration
    Nat Commun
    Huang W#, Feng Y#, Liang J#, Yu H, Wang C, Wang B, Wang M, Jiang L, Meng W, Cai W, Medvedovic M, Chen J, Paul C, Davidson WS, Sadayappan S, Stambrook PJ, Yu XY* and Wang Y*
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